They are caused by the build-up of crystals in the kidney which forms a hard stone-like lump. This is particularly striking when compared to the healthy kidney on the left. Kidney stones affect 1 in 10 people and may be caused by chronic infections or metabolic diseases. Photo by Dr Hassan Rashidi – Panel favourite – Staghorn calculus This image shows a three-dimensional reconstruction of the kidneys, with the right kidney having a large kidney stone, known as a ‘staghorn calculus’. It is hoped that one day we may be able to transfer cells like these, grown in a lab, into patients to help restore their sight. Photoreceptors are the cells in the retina, a thin layer of tissue in the back of our eye, that help us to detect light – and ultimately see. Retinal degenerative disorders are the leading cause of blindness worldwide, with debilitating life-long consequences for those affected. Photo by Christina Burke – Panel favourite – Flames of hope This image shows photoreceptors, which when stained generated an orange flame, grown in the lab from stem cells. Christina’s team hopes that using this imaging technique, known as chip cytometry, they will be able to better understand how T-cells interact with other cells within a tumour. Upon closer inspection, some T-cells are circled in a yellow ring, indicating a T-cell that is at risk of being over-stimulated and becoming ‘exhausted’. Immune cells, particularly T-cells, play a vital role in fighting cancer. These are part of the adaptive immune system and help fight infection. For example, the cells coloured in light blue that form what looks like a river running through the centre of the image, are T-cells. Winning Image – Leukocyte kaleidoscope This sea of blues and pinks captures the different immune cells, or leukocytes, flowing through the tonsil tissue at any one moment. Each leukocyte has a specific role to play within the tissue. The hospital’s pioneering research and treatment gives hope to children with the rarest, most complex and often life-threatening conditions. Great Ormond Street Hospital is one of the world’s leading children’s hospitals with the broadest range of dedicated, children’s healthcare specialists under one roof in the UK. Burke’s team are looking at images like this to better understand how T-cells interact with other cells within a tumour. Those surrounded by a yellow ring are at risk of becoming over-stimulated, or ‘exhausted’. Among the blues and pinks are T-cells, which play an important role in fighting cancer. The winning image, ‘Leukocyte Kaleidoscope’ entered by PhD student Christina Burke, shows immune cells in the tonsil tissue. These ranged from beautiful microscopy to intricate representations of data and photography. Staff from across the trust, including the National Institute for Health Research Great Ormond Street Hospital Biomedical Research Centre (NIHR GOSH BRC) and University College London Great Ormond Street Institute of Child Health (UCL GOS ICH), were invited to submit images that highlighted any aspect of their life-changing research that helps find treatments and cures for some of the most complex illnesses. Great Ormond Street Hospital for Children NHS Foundation Trust have just released the winners of their first research image competition ‘A moment of Research’. A stunning kaleidoscope of images revealed as winners of Great Ormond Street's first image awards
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |